Bioinspired stereoselective synthesis of chiral 2,5-diaryl-3,4-dimethyltetrahydrofurans from unprotected 1,4-diarylbutane-1,4-diols Rungrawin Chatpreecha, Chutima Kuhakarn, Pawaret Leowanawat, Vichai Reutrakul and Darunee Soorukram* A bioinspired stereoselective synthesis of (2,3-anti-3,4-syn-4,5-anti)-2,5-diaryl-3,4-dimethyltetrahydrofurans from unprotected chiral 1,4-diarylbutane-1,4-diols is described. Upon treatment of the chiral 1,4-diarylbutane1,4-diols with acid, chiral 2,5-diaryl-3,4-dimethyltetrahydrofurans were obtained in high yields and high stereoselectivity through the chemoselective formation of … Continue reading Bioinspired stereoselective synthesis of chiral 2,5-diaryl-3,4 dimethyltetrahydrofurans from unprotected 1,4-diarylbutane-1,4-diols